Precautions: Side effects associated with Panacur® Paste 10% could not be established in well-controlled safety studies in horses with single doses as high as 454 mg/lb (1,000 mg/kg) and 15 consecutive daily doses of 22.7 mg/b (50 mg/kg). Particularly with higher doses, the lethal action of fenbendazole may cause the release of antigens by the dying parasites. This phenomenon may result in either a local or systemic hypersensitive reaction. As with any drug, these reactions should be treated symptomatically. Panacur® Paste 10% has been evaluated for safety in pregnant mares during all stages of gestation with doses as high as 11.4 mg/lb (25 mg/kg) and in stallions with doses as high as 11.4 mg/lb (25 mg/kg). No adverse effects on reproductively were detected. The recommended dose for control of 4th stage larvae of Strongylus vulgaris, 4.6 mg/lg (10 mg/kg) daily for 5 consecutive days, has not been evaluated for safety in stallions or pregnant mares. Internal Parasites: Regular deworming at intervals of 6 to 8 weeks may be required due to the possibility of re-infection. Recommended Deworming Program: **December 1, February 1, April 1, June 1, August 1, October 1. The two treatments that are in bold type are the recommended periods when the 5 day treatment regimen for the control of the migrating larvae of S. vulgaris should be performed. **For other areas in the world, retreatment periods for the migrating larvae of S. vulgaris may be different; consult with you veterinarian. Cautions: Keep this and all medications out of the reach of children. When using Panacur Paste 10%, concomitantly with trichlorfon, refer to the manufacturer's label for use and cautions for trichlorfon. Warnings: Do not use in horses intended for food. Dosage: Administer orally at a rate of 2.3 mg/lb (5 mg/kg) for the control of large strongyles, small strongyles, and pinworms. One syringe will deworm a 1,100 lb horse. For foals and weanlings (less than 18 months of age) where ascarids are a common problem, the recommended dose is 4.6 mg/lb (10 mg/kg); one syringe will deworm a 550 lb horse. For control of encysted early 3rd stage (hypobiotic), late 3rd stage and 4th stage cyathostome larvae and 4th stage larvae of Strongylus vulgaris, the recommended dose is 4.6 mg/lb (10 mg/kg) daily for 5 consecutive days; administer one syringe for each 550 lbs body weight per day. Directions for Use: (1) Determine the weight of the horse. (2) Remove syringe tip. (3) Turn the dial ring until the edge of the ring nearest the tip lines up with zero. (4) Depress plunger to advance paste to tip. (5) Now set the dial ring at the graduation nearest the weight of the horse (do not underdose). (6) Horse's mouth must be free of food. (7) Insert nozzle of syringe through the interdental space and deposit the paste on the back of the tongue by depressing the plunger. How supplied: Panacur Paste 10% Equine Dewormer is supplied in 25 g syringes. Storage: Store in original container at or below 77degree F. Consult you veterinarian for assistance in the diagnosis, treatment and control of parasitism. |
